Clinical Evidence

Clinical Research conducted on DYSIS

Details of the various clinical trials and peer reviewed publications are available below. The US Federal Regulations restricts the display of certain non-US clinical data. Please declare your home country by selecting the appropriate tab below.

Testimonials

Dr Fellenbaum tells us how the DYSIS Colposcope has helped to offer his patient's the best care possible.
Dr Theodore FellenbaumFlint OBGYNPlay Video  Dr Theodore Fellenbaum

Testimonials

Women’s Care Florida adopted a DYSIS Colposcope to improve their standard of care. Dr Kapitz tells us how it has improved cervical…
Dr KapitzWomen's Care FloridaPlay Video  Dr Kapitz

Testimonials

Donovan Miske tells us how the DYSIS Colposcope has increased the level of care across all 3 of the practice locations.
Donovan Miske – Practice ManagerFlint OB/GYN (Flint, MI)Play Video  onovan Miske – Practice Manager
US Federal Regulations restrict the display on certain non-US clinical data.

Published Articles/Abstracts

Patient experience & reassurance after colposcopy with DYSIS

Date: 02/05/2016

Poster Presentation - BSCCP 2016

More >

Challenges and improvements in colposcopy on a post-treatment patient with carcinoma in situ

Date: 09/03/2015

More >

Challenges and improvements in colposcopy on a post-treatment patient with carcinoma in situ

Date: 09/03/2015

More >

Dynamic Spectral Imaging for Post-Treatment Triage

Date: 26/05/2014

Poster Presentation at IFCPC (London, 2014)

More >

The correlation between size of colposcopic lesions and the histological grade, using various colposcopy methods

Date: 26/05/2014

Poster presentation at IFCPC (London, 2014)

More >

Dynamic Spectral Imaging for triage of Low Grades

Date: 26/05/2014

Poster Presentation at IFCPC (London, 2014)

More >

Dynamic Spectral Imaging for Post-Treatment Triage

Date: 26/05/2014

Poster Presentation at IFCPC (London, 2014)

More >

The correlation between size of colposcopic lesions and the histological grade, using various colposcopy methods

Date: 26/05/2014

Poster presentation at IFCPC (London, 2014)

More >

Dynamic Spectral Imaging for triage of Low Grades

Date: 26/05/2014

Poster Presentation at IFCPC (London, 2014)

More >

Adjunctive colposcopy technologies for examination of the uterine cervix

Date: 17/03/2013

Adjunctive colposcopy technologies for examination of the uterine cervix

More >

Adjunctive colposcopy technologies for examination of the uterine cervix

Date: 17/03/2013

Adjunctive colposcopy technologies for examination of the uterine cervix

More >

NICE Guidance Document

Date: 11/12/2012

NICE Guidance Document.

More >

NICE Guidance Document

Date: 11/12/2012

NICE Guidance Document.

More >

Digital Colposcopy ready for use?

Date: 11/01/2009

Digital Colposcopy ready for use?

More >

Clinical Trials

Cervical Screening Wales

Date: 16/05/2018

Budithi et al, GOI 2018 DYSIS underwent an evaluation in Wales, where it was used at five colposcopy units and by several colposcopists as part of their routine practice. Purpose: To evaluate the implementation of colposcopy with DSI to routine practice in five clinics across […]

More >

Cervical Screening Wales

Date: 16/05/2018

Budithi et al, GOI 2018 DYSIS underwent an evaluation in Wales, where it was used at five colposcopy units and by several colposcopists as part of their routine practice. Purpose: To evaluate the implementation of colposcopy with DSI to routine practice in five clinics across […]

More >

IMPROVE-COLPO II

Date: 28/09/2017

DeNardis et al, International Journal of Women’s Health 2017 Overview: This publication presents sub-analysis results from the IMPROVE-COLPO study that was designed to assess the detection of women with high-grade cervical lesions when using the DYSIS digital colposcope with dynamic spectral imaging, in routine colposcopy […]

More >

IMPROVE-COLPO II

Date: 28/09/2017

DeNardis et al, International Journal of Women’s Health 2017 Overview: This publication presents sub-analysis results from the IMPROVE-COLPO study that was designed to assess the detection of women with high-grade cervical lesions when using the DYSIS digital colposcope with dynamic spectral imaging, in routine colposcopy […]

More >

IMPROVE-COLPO I

Date: 20/09/2017

Cholkeri-Singh et al, Journal of the Lower Genital Tract Disease (in press) Overview: This publication presents results from the IMPROVE-COLPO, which was designed to observe changes in practice and outcomes after the adoption of the DYSIS digital colposcope with dynamic spectral imaging, in routine colposcopy […]

More >

IMPROVE-COLPO I

Date: 20/09/2017

Cholkeri-Singh et al, Journal of the Lower Genital Tract Disease (in press) Overview: This publication presents results from the IMPROVE-COLPO, which was designed to observe changes in practice and outcomes after the adoption of the DYSIS digital colposcope with dynamic spectral imaging, in routine colposcopy […]

More >

Cervical Cancer Case Study

Date: 28/09/2016

Livingston and Papagiannakis, Case Reports in Obstetrics and Gynecology, 2016 Overview: A cervical cancer case study, that is used as an example to discuss some of the limitations of conventional colposcopy. Purpose: To study and discuss the unusual visual characteristics of a cervical cancer. Design: […]

More >

Cervical Cancer Case Study

Date: 28/09/2016

Livingston and Papagiannakis, Case Reports in Obstetrics and Gynecology, 2016 Overview: A cervical cancer case study, that is used as an example to discuss some of the limitations of conventional colposcopy. Purpose: To study and discuss the unusual visual characteristics of a cervical cancer. Design: […]

More >

Coronado et al, EJOG, 2015

Date: 15/10/2015

This is the first publication of results achieved with DYSIS during “real life” colposcopy. All patients were examined by a single experienced colposcopist, following standard practice rather than a strict study protocol.

More >

Coronado et al, EJOG, 2015

Date: 15/10/2015

This is the first publication of results achieved with DYSIS during “real life” colposcopy. All patients were examined by a single experienced colposcopist, following standard practice rather than a strict study protocol.

More >

Louwers et al, GynOnc, 2015

Date: 14/10/2015

An article presenting a different analysis of the results of the DYSIS clinical trial in the Netherlands was just published on Gynecologic Oncology. This study separates the patients in different groups according to their referral results, and shows that the sensitivity of colposcopy with DYSIS is high across all different groups. This is in contrast to conventional colposcopy that is rather poor on patients with milder cytologic abnormalities, who represent the vast majority of colposcopy referrals and their management is a major concern. Further, the study analyses the data for different patient referral pathways, and illustrates that DYSIS Colposcopy fits perfectly in the modern era of screening for cervical cancer where HPV testing plays a big role.

More >

Louwers et al, GynOnc, 2015

Date: 14/10/2015

An article presenting a different analysis of the results of the DYSIS clinical trial in the Netherlands was just published on Gynecologic Oncology. This study separates the patients in different groups according to their referral results, and shows that the sensitivity of colposcopy with DYSIS is high across all different groups. This is in contrast to conventional colposcopy that is rather poor on patients with milder cytologic abnormalities, who represent the vast majority of colposcopy referrals and their management is a major concern. Further, the study analyses the data for different patient referral pathways, and illustrates that DYSIS Colposcopy fits perfectly in the modern era of screening for cervical cancer where HPV testing plays a big role.

More >

IMPROVE (US Clinical Study)

Date: 01/01/2015

DySIS Medical is currently engaged in the largest ever colposcopy trial to be done in the US. 50 sites are recruiting around 9,000 patients to compare the impact of DySIS Colposcopy in comparison to conventional colposcopy.

More >

Coronado et al, GOI, 2014

Date: 11/11/2014

Dr. Pluvio Coronado explores how the relationship between colposcopist experience and sensitivity to detecting CIN2+ lesions changes when the DYSIS Colposcope is used.

More >

Coronado et al, GOI, 2014

Date: 11/11/2014

Dr. Pluvio Coronado explores how the relationship between colposcopist experience and sensitivity to detecting CIN2+ lesions changes when the DYSIS Colposcope is used.

More >

Zaal et al, BJOG, 2012

Date: 03/02/2012

Dr Afra Zaal investigates the sensitivity of DYSIS Colposcopy to detecting CIN2+ lesions in patients who tested positive for HPV-16.

More >

Zaal et al, BJOG, 2012

Date: 03/02/2012

Dr Afra Zaal investigates the sensitivity of DySIS Colposcopy to detecting CIN2+ lesions in patients who tested positive for HPV-16.

Dr Zaal finds that DySIS Colposcopy has 97% sensitivity and 100% specificity to HPV-16 lesions.

More >

Louwers et al, BJOG, 2010

Date: 23/12/2010

Dr Jacqueline Louwers compares the sensitivity of detecting CIN2+ with DYSIS Colposcopy in comparison to conventional colposcopy.

More >

Louwers et al, BJOG, 2010

Date: 23/12/2010

Dr Jacqueline Louwers compares the sensitivity of detecting CIN2+ with DySIS Colposcopy in comparison to conventional colposcopy.

The results favour DySIS Colposcopy a sensitivity of 88% in comparison to 55% for conventional colposcopy.

More >

Soutter et al, CCR, 2009

Date: 17/02/2009

Professor Pat Soutter conducted a clinical trail to establish the performance of the DySISmap in comparison to conventional colposcopy.

DySISmap detects 62% more women with CIN2+ disease.

More >