Challenges and improvements in colposcopy on a post-treatment patient with carcinoma in situ
Women treated for cervical dysplasia are co-tested (cytology/high-risk human papillomavirus) at 12/24 months. Those with a positive result are referred for colposcopy and continue to be monitored as dysplasia progression risk remains elevated.
A 56-year old woman with a history of excisional treatments, abnormal screening tests and persistent low-grade disease had colposcopy following high-grade cytology. She was examined using the DYSISTM Dynamic Spectral Imaging (DSI) map adjunctively to clinical judgment. Colposcopy was satisfactory and two punch biopsies revealed CIN1; given patient history and age, and corroborated by a large area of positive DSI mapping of the acetowhitening, cold knife conization was performed, which revealed carcinoma in situ in the most intense area of the map.
Colposcopy on healing epithelium is challenging as cervical morphology differs; in this case, using the DSI mapping adjunctively to colposcopy helped standardize and improve diagnostic and management decisions, reducing risks for the patient.
The full Case Study report can be read here.
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